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Pancreatic Cancer

Genetic screening for pancreatic cancer can reveal if you're at increased risk, often before symptoms appear. Take control early.

Genes Tested:

ATM
BRCA1
BRCA2
MLH6
CDKN2A
CHEK2
PALB2
SMAD4
STK11
TP53
10th

Pancreatic cancer is the 10th most commonly cancer in the UK

Symptoms often appear late when surgery is no longer an option according to the WHO.

9.5%

Chance of developing pancreatic cancer for people who carry certain ATM pathogenic variants.

inherited mutations (like BRCA2, CDKN2A, PALB2) account for about 10% of pancreatic cancers.

~1 in 2

Of all pancreatic cancer cases are diagnosed in people over the age of 75.

Identifying an inherited risk can help you take proactive steps to reduce your risk. According to UKCGG guidelines.

10,000

Over 10,000 cases of pancreatic cancer are diagnosed in the UK each year

Identifying an inherited risk can help you take proactive steps to reduce your risk.

What is Pancreatic Cancer?

Pancreatic cancer occurs when abnormal cells in the pancreas grow and divide uncontrollably, forming a tumour. The pancreas is a gland located behind the stomach that helps with digestion and regulates blood sugar by producing hormones like insulin. Pancreatic cancer often develops without early warning signs, which can make it difficult to detect in the early stages.

The symptoms of pancreatic cancer can include:

  • Unexplained weight loss
  • Persistent pain in the abdomen or back
  • Loss of appetite
  • Jaundice (yellowing of the skin and eyes)
  • Changes in stool (pale or greasy stools)
  • New-onset diabetes or worsening existing diabetes
  • Fatigue

These symptoms are common to many less serious conditions, but if they are new, persistent, or frequent, it’s important to see a doctor. Early diagnosis can make a big difference to treatment outcomes. If you are experiencing any symptoms that are worrying you, it is important that you report this to your GP.

More information about pancreatic cancer can be found on the Macmillan website.

What are the causes?

Usually, when someone is diagnosed with cancer, the cause is unknown. Contributing factors may include age, family history, environment, lifestyle and hormonal factors.

In some cases, genetic testing can identify a change (variant) in a single gene that causes a person to have an increased risk of developing certain cancers over their lifetime. These gene changes can be passed down through families.

Inherited genetic mutations account for about 5-10% of pancreatic cancers. Mutations in genes such as BRCA2, PALB2, ATM, and others significantly increase the average lifetime risk of developing the disease.

Is genetic testing for pancreatic cancer risk genes right for me?

Some people with a personal diagnosis or strong family history of pancreatic cancer, or related cancers, such as breast cancer, ovarian cancer or melanoma, may choose to consider genetic testing to try and identify a cause for their diagnosis or their family history.

Identifying a variant in a cancer gene can help clarify personal risk of developing certain cancers and inform your risk management options.

Genetic testing can provide very useful information, but may not be the right choice for everyone. Speaking to a genetic counsellor can help you explore your personal and family history, understand what testing might mean for you and your family, and help you make a decision that feels right for you.

Disclaimer! The information provided in this article is for educational purposes only and is based on NHS recommendations. It is not a substitute for professional medical advice. Always consult your doctor or a qualified healthcare provider for advice on medical conditions or treatments.

Genetic
Counselling

Cancer Risk Panel options

Cancer Risk Screening

Turnaround

17

-

21

days

Genes
50
Book £
660

Breast Cancer Risk Screening

Turnaround

17

-

21

days

Genes
13
Book £
660

Ovarian Cancer Risk Screening

Turnaround

17

-

21

days

Genes
14
Book £
660

BRCA Testing

Turnaround

17

-

21

days

Genes
2
Book £
660

What do we test for?

Know your genes, protect your future. Over 5,000 diseases are linked to genetic mutations. Early insights through genetic testing can help with prevention, early detection and personalised healthcare decisions.

Frequently Asked Questions

Does pancreatic cancer show in blood tests?

Some blood tests, like CA 19-9, may detect signs of pancreatic cancer, but they’re often not reliable for early detection.

That’s where preventative genetic testing can help. Inherited mutations in genes like BRCA2, PALB2, and ATM can increase your risk, even before symptoms appear. Jeen’s at-home DNA test checks for these changes and provides expert guidance, so you can take informed, proactive steps for your health.

How much is private genetic testing for pancreatic cancer in the UK?

At Jeen, private genetic testing for pancreatic cancer costs £660. This includes a high-quality at-home DNA test, lab analysis using clinical-grade sequencing, and a full genetic counselling with one of our expert counsellors.

The test analyses 50 carefully chosen genes, each backed by strong scientific evidence linked to prostate cancer risk. There are no hidden fees, just clear, trusted results and personalised guidance to help you understand your risk and take control of your health.

What is the strongest predictor of pancreatic cancer?

One of the strongest predictors of pancreatic cancer is carrying inherited gene mutations. Changes in genes like BRCA2, PALB2, ATM, CDKN2A, and STK11 can significantly increase your risk, even without symptoms or a clear family history.

Jeen’s at-home genetic test screens for these key genes using clinical-grade technology, giving you clear answers and expert support to take proactive steps early.

How early can genetic testing detect pancreatic cancer risk?

Genetic testing can reveal your inherited risk for pancreatic cancer at any stage, even years before symptoms appear. Because mutations like BRCA2, PALB2, or ATM are present from birth, testing offers an early opportunity to plan ahead.

At Jeen, our at-home test screens 50 clinically relevant genes, helping you take proactive steps like enhanced screening or prevention, long before cancer has a chance to develop.

How do I find a specialist or genetic counselor for pancreatic cancer testing?

With Jeen, you’ll have direct access to genetic counsellors who specialise in cancer risk, no waiting lists or referrals needed.

From understanding if testing is right for you to explaining your results, we’re with you every step of the way. And if you need ongoing care, we can help connect you to trusted specialists. It’s personalised, clear, and built around you.

What genes are linked to pancreatic cancer?

Several inherited gene mutations are linked to a higher risk of pancreatic cancer. These include BRCA1, BRCA2, PALB2, ATM, CDKN2A, and STK11. Some of these genes are also linked to breast, ovarian, and colorectal cancer.

At Jeen, our at-home genetic test screens for key inherited changes across multiple cancer-related genes, giving you clear insights into your risk and helping you take action early, with expert support at every step.

Where can I get genetic testing for pancreatic cancer in London?

If you're in London, you can access private pancreatic cancer genetic testing in the UK with Jeen, all from home. We send you a high-quality cheek swab kit, and your DNA is analysed in a certified US lab using clinical-grade sequencing.

Our expert genetic counsellors guide you through your results and next steps. Whether you're in central London or beyond, Jeen offers trusted, convenient testing with clear, personalised support.

How long does it take to get results from genetic testing for pancreatic cancer?

At Jeen your results are typically ready within four weeks. After you complete your at-home buccal swab and return it, your sample is analysed using advanced 50x sequencing in a certified lab.

Once your results are ready, you’ll have a one-to-one consultation with a genetic counsellor to explain what the results mean and help plan your next steps, so you can move forward with clarity and confidence.

Are there any warning signs that mean I should get tested for pancreatic cancer genes?

Yes, a strong family history of pancreatic cancer, especially if diagnosed young or in multiple relatives, is a key reason to consider testing.

At Jeen, our at-home genetic test makes it easy to uncover inherited risks, with expert support to guide your next steps.

Is it worth getting genetic testing for pancreatic cancer?

Yes, genetic testing for pancreatic cancer is absolutely worth it, especially if you have a family history or want to understand your risk early. Inherited mutations in genes like BRCA2, ATM, PALB2, and others can significantly increase your risk of developing pancreatic cancer, even if you have no symptoms.

These same genetic mutations are often linked to other cancers as well, including breast cancer, ovarian cancer, prostate cancer, and melanoma cancer. At Jeen, our at-home DNA test provides accurate insights across multiple cancer types, with expert guidance to help you take proactive steps before cancer has a chance to develop.  

Type of Cancers

Type of Cancers

We offer expert advice and testing for a range of genes that may increase your risk of developing certain types of cancer.

View Full Gene List

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