The most common cancer in men in the UK, it often runs in families. Prostate cancer genetic testing helps you understand your inherited risk early.
Porstate cancer is the 2nd most common cancer in the UK, and the most common for men.
Making it extremely common at older age - but many may never develop symptoms.
Making the incidence 100% more likely than the general population. This link is largely unexplained by genetics.
However, for metastatic prostate cancer, the survival drops to around 30%.
Disclaimer! The information provided in this article is for educational purposes only and is based on NHS recommendations. It is not a substitute for professional medical advice. Always consult your doctor or a qualified healthcare provider for advice on medical conditions or treatments.
Prostate cancer is a disease where cells in the prostate gland grow in an uncontrolled way. These abnormal cells can form a lump or tumour, and in some cases, may spread to other parts of the body. The prostate is a small gland found only in men, located just below the bladder, and it plays a role in producing semen.
There are several types of prostate cancer, but most cases are adenocarcinomas, which start in the gland cells. Prostate cancer often grows slowly, and many men may not notice symptoms for years. However, some types can be more aggressive. Early detection is important, as prostate cancer caught early is often easier to treat and can lead to much better outcomes. This is why many are now considering prostate cancer genetic screening as part of a proactive approach to health.
If you have a family history of prostate cancer, or related cancers such as breast, ovarian, or pancreatic cancer, you may want to consider genetic testing. Inherited changes (mutations) in genes such as BRCA2, BRCA1, and HOXB13 can significantly increase the risk of developing prostate cancer, particularly aggressive types.
You could be at higher risk if you have two or more close relatives with prostate cancer, if family members were diagnosed at a younger age (under 55), or if you have a known inherited mutation in your family. Men of African-Caribbean descent also have a higher risk of developing prostate cancer and should be particularly aware. Research shows that about 5-10% of prostate cancers are linked to inherited genetic changes. Knowing your genetic risk can help guide decisions around early screening, monitoring, and preventive options.
These symptoms can also be caused by other prostate conditions, such as an enlarged prostate, but it’s important to get them checked by a doctor. Early detection can make a big difference in how prostate cancer is managed and treated.
Prostate cancer is caused by a combination of factors, including age (risk increases as men get older), family history, ethnicity, and lifestyle choices. Most cases develop without a clear cause, but genetics can play a major role. If you have a strong family history of prostate, breast, or ovarian cancer, you may carry an inherited genetic mutation such as BRCA2, which can significantly raise your risk. Men of African-Caribbean heritage are about twice as likely to develop prostate cancer compared to men of other backgrounds. Prostate cancer genetic screening can help uncover inherited risks and inform your future care.
The most common tests for detecting prostate cancer are a PSA (prostate-specific antigen) blood test and a digital rectal examination (DRE). PSA is a protein produced by the prostate, and high levels can be a sign of prostate cancer, although other conditions can also raise PSA levels. Further investigations, such as MRI scans and prostate biopsies, may be recommended if there are concerns. If you’re worried about inherited risk, prostate cancer genetic testing can look for mutations linked to prostate cancer, helping you and your healthcare team decide on the best monitoring and prevention plan.
Treatment for prostate cancer depends on the type, stage, and how aggressive the cancer is. For slow-growing cancers, active surveillance (careful monitoring without immediate treatment) may be advised. Other options include surgery to remove the prostate, radiotherapy to destroy cancer cells, hormone therapy to block the effects of testosterone, and chemotherapy for more advanced disease.
In cases where prostate cancer is linked to an inherited genetic mutation, treatment decisions may also consider family planning and preventative strategies. Your care team will work closely with you to choose the most appropriate approach, focusing on effective treatment while maintaining your quality of life.
We offer expert advice and testing for a range of genes that may increase your risk of developing certain types of cancer.
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Yes, genetic testing can find inherited changes in genes like BRCA1, BRCA2, ATM, and CHEK2 that may raise your risk of prostate cancer. Even without symptoms, these insights can help you take early action.
At Jeen, our at-home DNA test includes key genes linked to prostate cancer, breast cancer, ovarian cancer and other cancers, giving you a clearer view of your inherited risk and helping you make confident, proactive health decisions.
Hereditary and familial prostate cancer both run in families, but for different reasons. Hereditary prostate cancer is caused by specific inherited gene mutationslike BRCA1, BRCA2, or HOXB13.
Familial prostate cancer appears more often in families but isn’t linked to a known gene, it may be due to shared habits or low-risk genetic factors. Jeen’s DNA test helps reveal if your risk is inherited, so you can act early.
At Jeen, prostate cancer genetic testing is done using a simple at-home cheek swab (buccal swab), no needles or clinic visits needed.
Your DNA is analysed in accredited labs using high-depth sequencing to detect inherited gene changes like BRCA testing, and others. These tests are highly reliable and meet the same clinical standards used in hospitals, with expert guidance to help you understand what your results mean.
Jeen’s genetic testing for prostate cancer is priced at £660. This all-inclusive cost covers your at-home DNA kit, lab analysis using high-depth 50x sequencing, and a personalised consultation with one of our expert genetic counsellors.
The test analyses 50 carefully chosen genes, each backed by strong scientific evidence linked to prostate cancer risk. You’ll get accurate insights into your inherited risk and support to help you decide on next steps with no extra charges or referrals needed.
If your Jeen test shows a genetic mutation linked to prostate cancer, we’re here to guide you. Once your results are reviewed, you'll get a personalised report by email.
You can book a follow-up with your genetic counsellor within 24 hours. If we don’t hear from you, our team will follow up to make sure you get timely support and expert advice to plan your next steps with confidence.
If prostate cancer runs in your family, especially if it was diagnosed at a young age or affects multiple relatives, genetic testing is worth considering. It can reveal inherited gene changes like BRCA or ATM variants, that may increase your risk and guide your screening or treatment.
With Jeen, you get reliable answers from an at-home test, plus expert support to help you make informed decisions.
Jeen’s genetic testing for prostate cancer offers the most accurate way to assess inherited risk.
While PSA blood tests detect existing cancer, our test focuses on identifying mutations in key genes like BRCA1, BRCA2, ATM, and HOXB13 that significantly increase lifetime risk. Using advanced 50x sequencing technology, we deliver clinical-grade precision alongside expert genetic counselling to help you understand your results and take control of your health before symptoms appear.
Yes, prostate cancer can be hereditary. About 5–10% of cases are caused by inherited gene mutations, like those in BRCA1, BRCA2, or HOXB13. These mutations can raise your lifetime risk, sometimes leading to earlier or more aggressive cancers.
If prostate cancer runs in your family, genetic testing with Jeen can help uncover hidden risk and guide your screening and prevention plan.
Yes, genetic testing can help personalise treatment for prostate cancer, especially in advanced cases or those with a family history. Mutations in genes like BRCA1, BRCA2, ATM, and MSH2 can influence how the cancer responds to certain treatments. For example, BRCA mutations may make PARP inhibitors more effective.
At Jeen, our at-home DNA test checks for these genes, giving you and your heatlhcare provider clear insights to guide care with confidence.
Genetic testing is safe and non-invasive, but there are a few things to consider. You might receive a result that's hard to interpret, called a Variant of Uncertain Significance (VUS).
Learning you carry a high-risk mutation like BRCA2 can also be emotionally challenging, especially with implications for family. At Jeen, we provide expert counselling to help you understand your results, manage concerns, and make informed, confident choices.
Learn more about genetic testing statistics and terminology with Jeen.
Our team of expert Genetic Counsellors is here to help. Whether you're curious about testing, your results, or what’s right for you — we're just a message away.
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