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KNOVA NIPT

For those looking for extra detail, KNOVA NIPT offers advanced screening for rare syndromes, chromosomal differences and microdeletions all from a simple test you can take at home.

conditions checked:

Down's syndrome
patau syndrome
edwards' syndrome
Microdeletions
De Novo Mutations
7-10

Working days turnaround time for results, once sample reaches lab.

Fast lab processing means most parents receive their results within a few working days.

£950

All-inclusive cost

Includes the KNOVA NIPT test, secure sample collection, analysis, and a consultation with a midwife.

97.8%

KNOVA Detection rate for Down’s, Edwards’ and Patau’s syndromes.

Conditions like Trisomy 21, 18, and 13 can occur even without family history. Screening helps identify risk early in pregnancy.

1 in 150*

Pregnancies are affected by the conditions screened by KNOVA.

*This number is based on UK prevalence data for conditions screened by Fulgent's KNOVA NIPT.

Why choose KNOVA Full Panel NIPT?

KNOVA is ideal for parents who want the most detailed and comprehensive prenatal screening available.

  • Cutting-edge technology: Built by Fulgent Genetics, KNOVA uses next-generation sequencing to offer highly accurate results with a wide detection range.
  • Ideal for high-risk pregnancies: If your baby has a raised nuchal translucency (NT) or ultrasound concern, KNOVA provides detailed information that may help avoid invasive testing.
  • All-in-one test: There’s no “basic” version of KNOVA. Every test includes its full, extended panel so you never miss a key result.
  • Unmatched screening power: KNOVA screens for more conditions than any other NIPT.
  • Optional Gender Reveal: Find out your baby’s sex with over 99% accuracy, if you wish.

What conditions does KNOVA screen for?

KNOVA offers the broadest panel of any NIPT, detecting both chromosomal and monogenic conditions. It’s built with Fulgent’s industry-leading sequencing platform, capable of analysing over 18,000 human genes.

  • All major trisomies: Down’s (21), Edwards’ (18), Patau (13), plus rare trisomies (15, 16, 22)
  • Sex chromosome conditions: Turner and Klinefelter syndromes, and more
  • 56 single-gene (monogenic) disorders: Like Noonan syndrome, CHARGE, Cornelia de Lange, tuberous sclerosis, skeletal dysplasias.
  • 12 microdeletion syndromes: Including DiGeorge syndrome (22q11.2).

What are the limitations of KNOVA?

While KNOVA is the most complete prenatal screening available, it isn’t suitable for every pregnancy. KNOVA cannot be used in the following situations:

  • Twin or triplet pregnancies
  • Pregnancies with egg donation
  • Cases of vanishing twin syndrome
  • Mothers with a history of bone marrow or organ transplant
  • Parental mosaicism or chromosomal abnormalities

KNOVA is also a screening test, not a diagnostic one. If any result shows a high risk, you may still need further testing (like CVS or amniocentesis) to confirm the result.

Who Should Consider KNOVA NIPT?

KNOVA is recommended for parents who:

  • Want the most advanced and thorough genetic screening available.
  • Have seen a raised NT or abnormal findings on early ultrasound.
  • Prefer to avoid amniocentesis or CVS unless absolutely necessary
  • Want reassurance about rare genetic syndromes and single-gene conditions.
  • Have a family history of complex or unexplained conditions.

KNOVA is one of the most advanced NIPT in the UK, available through Jeen. Book your appointment today and take the next step in understanding your baby’s genetic health.

What Are My Blood Draw Options for KNOVA NIPT?

In line with our flexible, prevention-first approach, Jeen Health offers multiple convenient options for how you provide your DNA sample for KNOVA NIPT:

  1. Self-Arranged Blood Draw (Free): We'll send your KNOVA NIPT kit and you can then arrange your own blood draw with a local nurse, midwife, phlebotomy service, or clinic. Many patients ask their private GP, or maternity care provider to assist. Please ensure your provider is comfortable drawing into the NIPT-specific tubes supplied in your kit. If needed, we can share instructions.
    • Best if you already have a provider you trust
    • No added charge from Jeen, but you may need to pay your chosen provider directly
    • Nationwide availability across the UK and some EU region
  2. Jeen Clinic Network (+£40): Prefer a clinic-based option? Book a blood draw appointment at one of our 40+ trusted partner locations across the UK.
    1. Clinics in major cities including Brighton, Cambridge, London, Manchester, Birmingham, Leeds, Newcastle, Edinburgh, Bristol, Cardiff, and Belfast.
    2. Quick and easy appointments, often near transport hub
  3. Home Visit (+£65): Need maximum convenience? We’ll send a qualified nurse to your home to take your blood sample.
    1. Ideal for patients with mobility, time or privacy needs
    2. Available across most of the UK and appointments coordinated by our team

These sample collection options ensure NIPT is accessible on your terms.

Disclaimer! The information provided in this article is for educational purposes only and is based on NHS recommendations. It is not a substitute for professional medical advice. Always consult your doctor or a qualified healthcare provider for advice on medical conditions or treatments.

Comparison Table

PrenatalSafe Complete Plus and KNOVA options compared to help you choose the right test for your pregnancy.

KNOVA NIPT Focused Comparison

KNOVA Comprehensive NIPT

Condition PNS Complete Plus Knova
Test Performance & Logistics
Gestational Age Requirement 10 weeks 10 weeks
Turnaround Time from Lab arrival (working days) 17-21 days 7-10 days
Lab Location UK+EU USA
No Call Rate 2% 1.5%
Standard Chromosomal Conditions
Trisomy 21 (Down Syndrome)
Trisomy 18 (Edwards Syndrome)
Trisomy 13 (Patau Syndrome)
Trisomy 15 -
Trisomy 16 -
Trisomy 22 -
Fetal Sex Determination (Optional)
Sex Chromosome Aneuploidies
Turner Syndrome (45,X)
Klinefelter Syndrome (47,XXY)
Triple X Syndrome (47,XXX)
Jacob's Syndrome (47,XYY)
Microdeletions
DiGeorge Syndrome
1p36 Deletion Syndrome
Angelman Syndrome
Cri-du-chat Syndrome
Prader-Willi Syndrome
Wolf-Hirschhorn Syndrome
Jacobsen Syndrome
Langer-Giedion Syndrome
Smith-Magenis Syndrome
9p Deletion Syndrome
18p Deletion Syndrome
18q22.3 Deletion Syndrome
De Novo/Inherited Monogenic Conditions - Group L
Noonan Syndrome
Cornelia de Lange Syndrome
Osteogenesis Imperfecta
Stickler Syndrome
Rett Syndrome
Crouzon/Pfeiffer Syndrome
Cleidocranial Dysplasia
CHARGE Syndrome
Cardiofaciocutaneous Syndrome
Bohring-Opitz Syndrome
Sotos Syndrome
Tuberous Sclerosis (TSC1)
Tuberous Sclerosis (TSC2)
Craniosynostosis (TWIST1)
Craniosynostosis (EFNB1)
Craniosynostosis (ERF)
Craniosynostosis (TCF12)
Kabuki Syndrome
Smith-Lemli-Opitz (CDKL5)

All NIPT options

from 9 weeks

Aneuploidy NIPT

Turnaround

7

-

10

days

Conditions
3
Book £
295
from 10 weeks

PrenatalSafe 3 UK

Turnaround

2

-

4

days

Conditions
3
Book £
325
from 9 weeks

Panorama Basic

Turnaround

7

-

10

days

Conditions
9
Book £
355
from 9 weeks

Panorama Microdeletions

Turnaround

7

-

10

days

Conditions
13
Book £
525
from 9 weeks

Unity Complete Screen

Turnaround

17

-

21

days

Conditions
12
Book £
800
from 10 weeks

KNOVA

Turnaround

7

-

10

days

Conditions
42
Book £
950
from 10 weeks

PrenatalSafe Complete Plus

Turnaround

17

-

21

days

Conditions
32
Book £
1490

20 Min Midwife
Counselling

Frequently Asked Questions

What’s the difference between basic and advanced NIPT?

Basic NIPT screens for the three most common chromosomal conditions: Down’s syndrome (Trisomy 21), Edwards’ syndrome (Trisomy 18), and Patau’s syndrome (Trisomy 13). Advanced NIPT includes everything in the basic test, but can also check for sex chromosome conditions, some rare genetic deletions (called microdeletions), and can tell you the biological sex of the baby if you choose to know. At Jeen, our NIPT specialists will help you decide which version is right for you during your consultation.

Why do I need to send my scan before doing the NIPT?

We ask you to send us your pregnancy scan so our medical team can confirm that you’re at least 9/10 weeks pregnant (depending on the test you’ve chosen) and that the pregnancy appears to be developing as expected. By reviewing a recent scan performed within one week of your NIPT blood draw, our doctors can check that there are no early concerns before going ahead with your NIPT.

It’s also helpful to know that NIPT screens for specific genetic conditions only. It doesn’t look for physical or structural differences, such as heart defects or organ development issues, which are usually identified later in pregnancy through detailed ultrasound scans. Reviewing your early scan helps ensure NIPT is appropriate for you before moving forward.

Can I do NIPT at home?

Yes. At Jeen Health, the standard option is for you to arrange your blood test at home independently. If you prefer, we can organise your blood test for you for an additional fee.

Can NIPT tell me the sex of my baby?

Yes, NIPT can identify the baby’s biological sex with high accuracy, but this is completely optional. If you’d like to know, just let our team know during your consultation and if you’d rather not find out, we’ll make sure it’s not included in your report.

Is NIPT covered by the NHS?

At the moment, NIPT is only offered on the NHS in certain situations, such as when a standard screening test shows a higher chance of a genetic condition. At Jeen, we offer private NIPT testing with flexible options, fast results, and full clinical support, including expert guidance and convenient at-home appointments.

How long do KNOVA NIPT results take?

Your KNOVA NIPT results will usually be ready within 7–10 working days from the time your sample arrives at our partner lab. Once the results arrive our admin team will call and deliver the results to you as soon as they’re ready.

Please note that delays can occur during public holidays in both the UK and the US. If your results indicate that follow-up testing is needed for your partner, we’ll act quickly to keep everything moving smoothly. Our priority is to get you the answers you need without unnecessary delays, so you can make confident, informed decisions for your pregnancy.

When can I take the NIPT and is it safe?

You can take some NIPTs from 9 weeks into your pregnancy. However, KNOVA can be done only from 10 weeks of pregnancy. Before booking your test with Jeen, we ask you to send us a recent pregnancy scan, such as a dating or viability scan, so our team of specialists can confirm you’re eligible to proceed.

NIPT is completely safe for both you and your baby. It’s a non-invasive blood test that only requires a small sample from your arm, and there is no physical contact with the baby. This means there is no risk of miscarriage or harm to the pregnancy, unlike some invasive procedures.

How accurate is NIPT?

NIPT is over 99% accurate at detecting Down’s syndrome and is also highly reliable for Edwards’ and Patau’s syndromes. It is more accurate than standard NHS screening and produces fewer false-positive results, meaning fewer people are referred for unnecessary follow-up testing.

Visit our NIPT statistics page for more information.

Do I need midwife counselling before NIPT?

Yes. With Jeen, you must attend an online midwife NIPT counselling appointment before the test. After this appointment, we will send you the kit for sample collection.

At Jeen, we believe it’s important that everyone taking NIPT has the chance to speak to a qualified midwife (or a genetic counsellor for an additional fee) first. This session helps you understand what the test covers, what it doesn’t, and what the results might mean for you and your baby. It’s also a space to ask questions and make confident, informed choices.

What happens if my NIPT result is high risk?

If your result shows a high risk for a condition, we’ll arrange a follow-up session with one of our genetic counsellors to explain exactly what it means. You’ll be given the option to have a diagnostic test, such as amniocentesis or CVS, which can confirm the result. We’ll support you at every step, with clear information and no pressure.

Will NIPT detect all possible conditions?

No. While KNOVA is one of the most comprehensive NIPT options currently available, it does not test for all genetic conditions or birth defects.

NIPT, including advanced tests, focuses primarily on conditions caused by extra or missing chromosomes. Structural abnormalities (such as heart defects, brain anomalies, or limb differences) cannot be detected by NIPT and are usually identified through ultrasound scans.

Alongside KNOVA, another highly comprehensive option is PrenatalSafe Complete Plus. Both tests offer broader screening than standard NIPT options, but each has its own scope and limitations.You can choose your preferred test; however, we strongly recommend discussing your options during your midwife consultation, where your medical history, scan findings, and personal preferences will be reviewed to help determine the most appropriate screening for your pregnancy.

Regardless of which NIPT you choose, it is essential to attend all routine pregnancy scans and antenatal appointments, as these remain crucial for monitoring fetal development and identifying conditions that NIPT cannot detect.

‍Can I change my NIPT after booking?

No. KNOVA does not have a basic or reduced panel. It is offered as a single, comprehensive NIPT option.

If you are looking for a more basic NIPT option, you can choose one of the following instead: PrenatalSafe 3 UK, Aneuploidy NIPT and Panorama. Each of these tests has its own advantages and limitations, and the most suitable option for you may depend on your medical history, scan findings, and personal preferences.

You can change your NIPT choice following your counselling or midwife appointment. If you switch to a less expensive test, we will refund the price difference within 5–10 working days. If you decide to upgrade to a more advanced or higher-priced option, we will invoice you for the additional amount after your consultation.

Our midwife will help guide you through the options to ensure you choose the most appropriate screening for your pregnancy.

Please note: If you upgrade your test, your NIPT kit will only be sent once the additional invoice has been paid in full.

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