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Cancer
Genetic Testing

Personalised genetic testing and counselling
for hereditary cancers

Type of Cancers

Type of Cancers

Type of Cancers

We offer expert advice and testing for a range of genes that may increase your risk of developing certain types of cancer.

View Full Gene List

Statistics

In the UK, 1 in 2 people will be diagnosed with cancer at some point in their life. Genetic testing can help identify your risk of developing some of the most common types of cancer, so you can take action early.

Up to 10%

of all cancers are linked to inherited genetic changes — including some of the most common gender-specific cancers like breast cancer and prostate cancer.

Genetic Counselling

The Power of Pedigree

A key part of your test is a 45-minute personalised session with one of our genetic counsellors. Genetics can be complex, but you're not alone—we're here to guide you through it. By exploring your family history, we can uncover valuable insights that could make a real difference to your health.

The Test

Cancer Focus Panel

Our genetic cancer panel focuses on 50 carefully chosen genes, all backed by strong scientific evidence. While some tests look at more genes, many include ones with little clinical value. We focus on what’s most useful—so you get results you can actually act on.

The Lab

Fulgent Genetics - Trusted Partner

Fulgent Genetics, based in California, is a global leader in genetic testing and analysis. We’ve partnered with them because quality matters—especially when it comes to your health. Their state-of-the-art Illumina sequencing technology delivers over 99% accuracy at 50x coverage, ensuring your results are both reliable and clinically meaningful.

Research

World-class experts

Medicine is always evolving—and so are we. Our expert team stays up to date with the latest research and clinical guidelines, so you’re always getting advice that’s current, trusted, and tailored to you.

What's Next?

What happens if my DNA shows a higher-risk gene?

Gene List

Learn about our carefully selected list of
genes relating to higher cancer risk

Gene Group Genes Associated Cancers
DNA Mismatch Repair (MMR) MLH1, MSH2, MSH6, PMS2, EPCAM, MSH3, MLH3 Colorectal, endometrial, ovarian, gastric, small-intestine, urinary-tract
Homologous Recombination Repair (HRR) BRCA1, BRCA2, PALB2, ATM, CHEK2, RAD51C, RAD51D, BARD1, BRIP1 Breast, ovarian, pancreatic, prostate, gastric, other solid tumors
Adenomatous & Polyposis Genes APC, MUTYH, AXIN2, RNF43, GREM1, BMPR1A, SMAD4 Colorectal adenomas & carcinoma; duodenal/jejunal & gastric polyps
Polymerase-Proofreading Polyposis POLE, POLD1 Colorectal adenomas & carcinoma; endometrial carcinoma
Base Excision Repair (BER) NTHL1, MBD4 Colorectal adenomas & carcinoma; acute myeloid leukemia
Other High-Penetrance Syndromes TP53, CDH1, PTEN, STK11 Sarcoma, breast, brain, adrenocortical; diffuse gastric, lobular breast; Cowden: breast, thyroid, endometrial; PJS: pancreatic, GI, lung
Renal-Cancer Predisposition VHL, MET, FH, FLCN Clear-cell RCC, papillary RCC, leiomyomatosis-RCC, chromophobe RCC; hemangioblastomas, pheochromocytomas, lung cysts
Endocrine Tumor Syndromes MEN1, RET, CDKN1B Parathyroid, pituitary, pancreatic endocrine; medullary thyroid carcinoma; pheochromocytoma
Neurocutaneous Tumor Syndromes NF1, TSC1, TSC2 Neurofibromas, MPNST, glioma; SEGAs, renal angiomyolipomas
Paraganglioma/Pheochromocytoma Genes SDHA, SDHB, SDHC, SDHD, TMEM127, MAX Paragangliomas, pheochromocytomas, occasionally GIST
Other Cancer Predisposition CDKN2A, BAP1, HOXB13 Melanoma, pancreatic; mesothelioma, uveal melanoma, RCC; hereditary prostate cancer
Gene Group Genes Associated Cancers
DNA Mismatch Repair (MMR) MLH1, MSH2, MSH6, PMS2, EPCAM, MSH3, MLH3 Colorectal, endometrial, ovarian, gastric, small-intestine, urinary-tract
Homologous Recombination Repair (HRR) BRCA1, BRCA2, PALB2, ATM, CHEK2, RAD51C, RAD51D, BARD1, BRIP1 Breast, ovarian, pancreatic, prostate, gastric, other solid tumors
Adenomatous & Polyposis Genes APC, MUTYH, AXIN2, RNF43, GREM1, BMPR1A, SMAD4 Colorectal adenomas & carcinoma; duodenal/jejunal & gastric polyps
Polymerase-Proofreading Polyposis POLE, POLD1 Colorectal adenomas & carcinoma; endometrial carcinoma
Base Excision Repair (BER) NTHL1, MBD4 Colorectal adenomas & carcinoma; acute myeloid leukemia
Other High-Penetrance Syndromes TP53, CDH1, PTEN, STK11 Sarcoma, breast, brain, adrenocortical; diffuse gastric, lobular breast; Cowden: breast, thyroid, endometrial; PJS: pancreatic, GI, lung
Renal-Cancer Predisposition VHL, MET, FH, FLCN Clear-cell RCC, papillary RCC, leiomyomatosis-RCC, chromophobe RCC; hemangioblastomas, pheochromocytomas, lung cysts
Endocrine Tumor Syndromes MEN1, RET, CDKN1B Parathyroid, pituitary, pancreatic endocrine; medullary thyroid carcinoma; pheochromocytoma
Neurocutaneous Tumor Syndromes NF1, TSC1, TSC2 Neurofibromas, MPNST, glioma; SEGAs, renal angiomyolipomas
Paraganglioma/Pheochromocytoma Genes SDHA, SDHB, SDHC, SDHD, TMEM127, MAX Paragangliomas, pheochromocytomas, occasionally GIST
Other Cancer Predisposition CDKN2A, BAP1, HOXB13 Melanoma, pancreatic; mesothelioma, uveal melanoma, RCC; hereditary prostate cancer
DNA Mismatch Repair (MMR)
Genes:
MLH1, MSH2, MSH6, PMS2, EPCAM, MSH3, MLH3
Associated Cancers:
Colorectal, endometrial, ovarian, gastric, small-intestine, urinary-tract
Homologous Recombination Repair (HRR)
Genes:
BRCA1, BRCA2, PALB2, ATM, CHEK2, RAD51C, RAD51D, BARD1, BRIP1
Associated Cancers:
Breast, ovarian, pancreatic, prostate, gastric, other solid tumors
Adenomatous & Polyposis Genes
Genes:
APC, MUTYH, AXIN2, RNF43, GREM1, BMPR1A, SMAD4
Associated Cancers:
Colorectal adenomas & carcinoma; duodenal/jejunal & gastric polyps
Polymerase-Proofreading Polyposis
Genes:
POLE, POLD1
Associated Cancers:
Colorectal adenomas & carcinoma; endometrial carcinoma
Base Excision Repair (BER)
Genes:
NTHL1, MBD4
Associated Cancers:
Colorectal adenomas & carcinoma; acute myeloid leukemia
Other High-Penetrance Syndromes
Genes:
TP53, CDH1, PTEN, STK11
Associated Cancers:
Sarcoma, breast, brain, adrenocortical; diffuse gastric, lobular breast; Cowden: breast, thyroid, endometrial; PJS: pancreatic, GI, lung
Renal-Cancer Predisposition
Genes:
VHL, MET, FH, FLCN
Associated Cancers:
Clear-cell RCC, papillary RCC, leiomyomatosis-RCC, chromophobe RCC; hemangioblastomas, pheochromocytomas, lung cysts
Endocrine Tumor Syndromes
Genes:
MEN1, RET, CDKN1B
Associated Cancers:
Parathyroid, pituitary, pancreatic endocrine; medullary thyroid carcinoma; pheochromocytoma
Neurocutaneous Tumor Syndromes
Genes:
NF1, TSC1, TSC2
Associated Cancers:
Neurofibromas, MPNST, glioma; SEGAs, renal angiomyolipomas
Paraganglioma/Pheochromocytoma Genes
Genes:
SDHA, SDHB, SDHC, SDHD, TMEM127, MAX
Associated Cancers:
Paragangliomas, pheochromocytomas, occasionally GIST
Other Cancer Predisposition
Genes:
CDKN2A, BAP1, HOXB13
Associated Cancers:
Melanoma, pancreatic; mesothelioma, uveal melanoma, RCC; hereditary prostate cancer

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Cancer Risk Assessment Tool

Disclaimer! This tool provides approximate cancer risk estimates based on genetic and ethnic factors. It is for educational purposes only and should not replace professional medical advice. Risk estimates are based on population-level data and may not reflect your individual circumstances. Always consult a healthcare provider or genetic counsellor for personalised risk assessment and screening recommendations.

Cancer Risk Assessment Tool

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Our team of expert Genetic Counsellors is here to help. Whether you're curious about testing, your results, or what’s right for you — we're just a message away.

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