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PrenatalSafe Complete Plus NIPT

PrenatalSafe Complete Plus, is one of our most advanced non-invasive prenatal test (NIPT), screening for a broader range of chromosomal, genetic  and rare conditions in your baby.

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10-22 days

Typical turnaround time for results

Fast lab processing means most parents receive their results within a few working days.

£1490

All-inclusive cost

Includes the PrenatalSafe Complete Plus test, secure sample collection, analysis, and a consultation with a Jeen genetic counsellor.

>99%

PrenatalSafe Detection rate for Down’s, Edwards’ and Patau’s syndromes.

Conditions like Trisomy 21, 18, and 13 can occur even without family history. Screening helps identify risk early in pregnancy.

1 in 126*

Pregnancies are affected by the conditions screened by PrenatalSafe Complete Plus.

*This number is based on UK prevalence data for conditions screened by PrenatalSafe Complete Plus.

Table of contents

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Disclaimer! The information provided in this article is for educational purposes only and is based on NHS recommendations. It is not a substitute for professional medical advice. Always consult your doctor or a qualified healthcare provider for advice on medical conditions or treatments.

Why choose PrenatalSafe Complete Plus NIPT?

  • Widest screening available: Tests for a full spectrum of chromosomal and genetic conditions, including microdeletions and single-gene disorders.
  • High Accuracy: Detects over 99% of cases of Down’s syndrome (Trisomy 21), with similarly high detection rates for Edwards syndrome (Trisomy 18) and Patau syndrome (Trisomy 13).
  • Safe and Simple: Requires only a single tube of maternal blood; no risk to you or your baby.
  • Quick Results: Results are typically available within 2-5 working days.
  • Low Failure Rate: Less than 0.5% of tests fail to produce a result, reducing the need for repeat testing.
  • Optional Gender Reveal: Find out your baby’s sex with over 99% accuracy, if you wish.

What conditions does PrenatalSafe Complete Plus screen for?

  • Common trisomies: Down’s syndrome (Trisomy 21), Edwards syndrome (Trisomy 18) and Patau syndrome (Trisomy 13)
  • Sex chromosome conditions: Turner syndrome, Klinefelter syndrome and Other X/Y chromosomal changes
  • 9 microdeletion syndromes, including: DiGeorge syndrome (22q11.2 deletion), Cri-du-chat syndrome, Prader-Willi and Angelman syndromes
  • Over 200 single-gene disorders, such as: Noonan syndrome, Skeletal dysplasias, Cornelia de Lange syndrome and Kabuki syndrome
  • Optional Fetal Sex Determination: Know your baby’s sex early, if desired.

Full condition list available on request or during your genetic counselling session.

How does the PrenatalSafe Complete Plus work?

During pregnancy, small amounts of your baby’s DNA circulate in your bloodstream. PrenatalSafe Complete Plus uses whole-genome sequencing and targeted analysis to detect a wide range of chromosomal and genetic changes. It’s completely non-invasive and safe for both you and your baby.

Who Should Consider PrenatalSafe Complete Plus?

This test is suitable for any expectant parent who wants the most comprehensive genetic screening available. It’s especially recommended if:

  • You’re seeking the widest reassurance about your baby’s health.
  • You have a family history of genetic conditions or previous pregnancy loss.
  • You’re looking to avoid invasive procedures like amniocentesis.
  • You want to know more than what standard NIPTs offer.

Get peace of mind early in your pregnancy with the most advanced prenatal screening available in the UK.

Comparison Table

Basic and advanced PrenatalSafe options compared to help you choose the right test for your pregnancy.

PrenatalSafe Comparison - Basic vs Complete Plus

PrenatalSafe Comparison

Condition 3UK Basic Complete Plus
Test Performance & Logistics
Gestational Age Requirement ≥10 weeks ≥10 weeks
Turnaround Time (working days) 2-4 days 10-22 days
Lab Location UK UK + EU
No Call Rate 0.5% 0.5%
Redraw Rate 2% 2%
Standard Chromosomal Conditions
Trisomy 21 (Down Syndrome)
Trisomy 18 (Edwards Syndrome)
Trisomy 13 (Patau Syndrome)
Fetal Sex Determination (Optional)
Advanced Chromosomal Analysis
Sex Chromosome Aneuploidies
Rare Autosomal Aneuploidies
Genome-wide CNVs (>7MB)
Microdeletion Syndromes
DiGeorge Syndrome (22q11.2)
Prader-Willi Syndrome
Angelman Syndrome
Cri-du-Chat Syndrome
1p36 Deletion Syndrome
Wolf-Hirschhorn Syndrome
Smith-Magenis Syndrome
Jacobsen Syndrome
Langer-Giedion Syndrome
Inherited Monogenic Disorders
Noonan Syndrome (8 variants)
De Novo Monogenic Disorders
CHARGE Syndrome
Achondroplasia
Osteogenesis Imperfecta
Rett Syndrome
Stickler Syndrome
Crouzon/Pfeiffer Syndrome
Cornelia de Lange Syndrome
Alagille Syndrome
Sotos Syndrome
Bohring-Opitz Syndrome
Cardiofaciocutaneous Syndrome
Schinzel-Giedion Syndrome
Holoprosencephaly

Genetic
Counselling

Frequently
Asked Questions

What’s the difference between basic and advanced NIPT?

Basic NIPT screens for the three most common chromosomal conditions: Down’s syndrome (Trisomy 21), Edwards’ syndrome (Trisomy 18), and Patau’s syndrome (Trisomy 13). Advanced NIPT includes everything in the basic test, but can also check for sex chromosome conditions, some rare genetic deletions (called microdeletions), and can tell you the biological sex of the baby if you choose to know. At Jeen, our genetic counsellors will help you decide which version is right for you during your consultation.

Why do I need to send my scan before doing the NIPT?

We ask you to send us your scan so our medical team can confirm that you’re at least 10 weeks pregnant and that the pregnancy appears to be developing normally. This helps us ensure the test is appropriate and that the results will be accurate. It’s also important to understand that NIPT only screens for specific genetic conditions. It does not detect structural anomalies, such as heart defects or issues with organ development, which are physical rather than genetic. These types of conditions are usually picked up later in pregnancy through detailed ultrasound scans. Sending your early scan allows our doctors to check for any concerns before moving forward with the NIPT.

Can I do NIPT at home?

No - genetic testing shows your risk, not a guarantee. Some people with a genetic variant never develop the condition, while others without a variant might still be affected due to lifestyle or environmental factors.

Can NIPT tell me the sex of my baby?

Yes, NIPT can usually identify the baby’s biological sex with high accuracy, but this is completely optional. If you’d like to know, just let your genetic counsellor know during your consultation — and if you’d rather not find out, we’ll make sure it’s not included in your report.

Is NIPT covered by the NHS?

At the moment, NIPT is only offered through the NHS in certain cases — for example, if you’ve had a high-risk result from a standard screening test. At Jeen, we offer private NIPT testing with flexible options, fast results, and full clinical support, including at-home appointments and expert guidance.

How long does it take to get results?

Your results will usually be ready within 2–10 working days from the time your sample arrives at our partner lab. The exact turnaround time depends on which NIPT you’ve chosen and the location of the laboratory. We’ll keep you informed throughout the process and arrange a follow-up consultation to talk you through your results as soon as they’re ready.

Please note that delays can occur during public holidays in both the UK and the US. If your results indicate that follow-up testing is needed for your partner, we’ll act quickly to keep everything moving smoothly. Our priority is to get you the answers you need without unnecessary delays — so you can make confident, informed decisions for your pregnancy.

When can I take the NIPT and is it safe?

You can take the NIPT from 10 weeks into your pregnancy. Before booking your test with Jeen, we ask you to send us a recent pregnancy scan, such as a dating or viability scan, so our team of specialists can confirm you’re eligible to proceed.

Yes, NIPT is completely safe for both you and your baby. It’s a non-invasive blood test that only requires a small sample from your arm, and there is no physical contact with the baby. This means there is no risk of miscarriage or harm to the pregnancy, unlike some invasive procedures.

How accurate is NIPT?

NIPT is over 99% accurate at detecting Down’s syndrome and also highly reliable for Edwards’ and Patau’s syndromes. It is more accurate than standard NHS screening and produces fewer false positive results, which means fewer people are sent for unnecessary follow-up testing.

Do I need genetic counselling before NIPT?

Yes, at Jeen we believe it’s important that everyone taking NIPT has a chance to speak to a qualified genetic counsellor first. This session helps you understand what the test covers, what it doesn’t, and what the results might mean for you and your baby. It’s a space to ask any questions and make confident, informed choices.

What happens if my NIPT result is high risk?

If your result shows a high risk for a condition, we’ll arrange a follow-up session with one of our genetic counsellors to explain exactly what it means. You’ll be given the option to have a diagnostic test, such as amniocentesis or CVS, which can confirm the result. We’ll support you at every step, with clear information and no pressure.

Will NIPT detect all possible conditions?

No, NIPT screens for a specific set of genetic conditions, mostly involving extra or missing chromosomes. It won’t detect all birth defects or structural anomalies, such as heart defects or limb differences. That’s why it’s important to still attend all your routine scans and check-ups during pregnancy.

NIPT Testing Options

NIPT gives you a safe and early look at your baby’s health, explore the conditions we can screen for during pregnancy.

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